Plantago major protective effects on antioxidant status after administration of 7,12-dimethylbenz(a)anthracene in rats
Tarih
2011Yazar
Oto, G. and Ekin, S. and Ozdemir, H. and Demir, H. and Yasar, S. and Levent, A. and Berber, I. and Kaki, B.
Üst veri
Tüm öğe kaydını gösterÖzet
Aim: The present study was designed to evaluate effects of Plantago major extract on oxidative status in Wistar albino rats administrated 7,12-dimethylbenz(a)anthracene (DMBA). Methods: Rats were divided into three equal groups of 6 animals each: Group 1 controls, group 2 treated with DMBA (100 mg/kg, single dose) and group 3 receiving the DMBA and the aqueous extract at 100 mg/kg/d for 60 days. Results: Significant decrease in catalase (P<0.05), carbonic anhydrase (p≤0.01), reduced glutathione (GSH) (P<0.01) and total protein (P<0.01) values was observed in the DMBA group compared with the healthy controls and DMBA + Plantago major groups. Conclusion: The results suggest preventive effects of Plantago major on DMBA induced oxidative damage in Wistar albino rats that might be due to decreased free radical generation.
Bağlantı
https://www.scopus.com/inward/record.uri?eid=2-s2.0-79958782513&partnerID=40&md5=e1859740eb9ffbb516d12c47ddc32a8bhttp://acikerisim.bingol.edu.tr/handle/20.500.12898/5056
Koleksiyonlar
DSpace@BİNGÖL by Bingöl University Institutional Repository is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 Unported License..