dc.contributor.author | Oto, G. and Ekin, S. and Yaşar, S. and Özdemir, H. and Yur, F. | |
dc.date.accessioned | 2021-04-08T12:10:27Z | |
dc.date.available | 2021-04-08T12:10:27Z | |
dc.date.issued | 2011 | |
dc.identifier.issn | 16845315 | |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-79959336037&partnerID=40&md5=1366abb7a150f1b99dca18d3e0ba3b43 | |
dc.identifier.uri | http://acikerisim.bingol.edu.tr/handle/20.500.12898/5022 | |
dc.description.abstract | This study was designed to evaluate the effect of CoQ10 and vitamin E on serum total sialic acid (TSA), lipid bound sialic acid (LSA) and some elements in rat administered doxorubicin (DXR). Cu levels were increased in the group treated with DXR + vitamin E in comparison with DXR (p<0.05) and CoQ10 groups (p = 0.001). Furthermore, copper levels were increased in the group treated with DXR + CoQ10 in comparison with CoQ10 group (p < 0.05). Zn levels were decreased in the group treated with DXR + vitamin E in comparison with CoQ10 group (p < 0.05). Mg levels were decreased in subjects treated with DXR + vitamin E in comparison with the control group values (p < 0.05). Particularly, the observed increase in Cu levels in rats from DXR + vitamin E group might be due to the decrease of vitamin E. However, the oxidative damage could be as a result of DXR occurence and may be helpful to clinicians in chemotherapy using anthracycline. © 2011 Academic Journals. | |
dc.language.iso | English | |
dc.source | African Journal of Biotechnology | |
dc.title | The effect of CoQ10 and vitamin E on serum total sialic acid, lipid-bound sialic acid, some trace elements and minerals in rats induced with doxorubicin | |