Oxidative stress biomarkers of exposure to deltamethrin in rainbow trout fry (oncorhynchus mykiss)
Date
2011Author
Yonar, S.M. and Sakin, F. and Yonar, M.E. and Ispir, Ü. and Kinci, M.
Metadata
Show full item recordAbstract
Deltamethrin (DM) is a widely used pesticide based on pyrethroids, and is reported to be extremely toxic to fish species. We investigated the effect of DM concentrations (0.010, 0.0125 and 0.0250 μg/L) on antioxidants in rainbow trout, Oncorhynchus mykiss, using standard laboratory conditions. 24 h exposure caused whole body induction of various antioxidant enzymes and nonenzymatic antioxidants. Results showed that DM significantly (p< 0.05) increased malondialdehyde (MDA) levels. Catalase (CAT) activity decreased in all experimental groups. Glutathione (GSH) was significantly (p<0.05) increased in the group with DM concentration of 0.0250 μg/L DM for 24 h. The activity of glutathione peroxidase (GSH-Px) was found to be statistical significantly (p<0.05) decreased in all other experimental groups except the 0.010 μg/L DM treated group. The parameters studied in this investigation can also be used as biomarkers of exposure to DM. It is suggested that appropriate ecotoxicological risk assessments should be made wherever DM is proposed for use in pest control activities. © by PSP.
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-80052390559&partnerID=40&md5=8379031e2c713b531f509defee6f3a0ehttp://acikerisim.bingol.edu.tr/handle/20.500.12898/5005
Collections
DSpace@BİNGÖL by Bingöl University Institutional Repository is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 Unported License..