Treatment of naturally occuring squamous cell carcinomas with mixed therapy plus tetracycline in dogs

Abstract

The objectives of this study were to determine the possible effects of mixed therapy plus the application of tetracycline on Squamous Cell Carcinomas (SCC) in dogs. Ten Anatolian shepherd dogs (Kangal dogs) with naturally occurring SCC were treated with Tetracycline (TC) both topically and parenterally for 6 weeks. TC was applied topically in a zinc pomade with miscellaneous agents including salicylic acid betamethasone and zinc oxyde plus vaseline and parenterally via intravenous injection at a dose of 3 mL/kg/day for 10 days. The healing effects of this treatment procedure were measured by histopathological observations. At the end of 3 weeks, three dogs (30%) showed significant improvement and no tumor recurrence after treatment. © Medwell Journals, 2013.