• Türkçe
    • English
  • Türkçe 
    • Türkçe
    • English
  • Giriş
Öğe Göster 
  •   DSpace Ana Sayfası
  • 6.Araştırma Çıktıları / Research Outcomes(WOS-Scopus-TR-Dizin-PubMed)
  • Scopus İndeksli Yayınlar Koleksiyonu
  • Öğe Göster
  •   DSpace Ana Sayfası
  • 6.Araştırma Çıktıları / Research Outcomes(WOS-Scopus-TR-Dizin-PubMed)
  • Scopus İndeksli Yayınlar Koleksiyonu
  • Öğe Göster
JavaScript is disabled for your browser. Some features of this site may not work without it.

Effect of lipoic acid on the some elements in brain tissue of DMBA-induced Guinea Pigs [DMBA i̇le i̇ndüklenmiş kobayların beyin dokusundaki bazı elementler üzerine alfa lipoik asidin etkisi]

Thumbnail
Tarih
2009
Yazar
Çiftçi, H. and Özkaya, A. and Dayanga̧, A. and Ölçücü, A. and Çelik, S. and Şahin, Z. and Ateş, S.
Üst veri
Tüm öğe kaydını göster
Özet
The oxidative stress, depending on many factors in the etiology of developing cancer caused by reactive oxygen species, plays an important role. In our study, 7, 12-dimethylbenz-[a]anthracene (DMBA) was applied in Guinea Pigs, the alpha lipoic acid (α-LA) has antioxidant properties was investigated protective role against to levels of macro and trace elements in brain. In experiments; totally 24 adult male Guinea Pigs were randomly divided into 4 equal groups (control, DMBA, α-LA and DMBA+α-LA) containing same numbers. As a result of the analysis in Guinea Pigs brain with the aid of ICP-AES; it was found that the level of calcium from macro elements in DMBA group increased according to control group (P<0.01) and decreased in DMBA+α-LA group (P<0.01), that was in the same levels with control group. Magnesium decreased in DMBA group according to control group (P<0.01) and DMBA+α-LA group and increased in close level of control group. Regarding trace elements, it was seemed that copper levels compared with the control group decreased in DMBA group (P<0.01) and DMBA+α-LA group, it was same level with control group. It was observed that the level zinc decreased according to control group in DMBA group (P<0.01) and increased in DMBA+α-LA group (P<0.01). In addition, it was obtained that levels of iron and manganese in between groups were not significant (P>0.05). As a result, it can be said that from the point of macro and trace elements, the lipoic acid (α-LA) was indicated neuroprotective effect for protection of important organs such as brain from the oxidative stress.
Bağlantı
https://www.scopus.com/inward/record.uri?eid=2-s2.0-70349502299&doi=10.9775%2fkvfd.2009.067-a&partnerID=40&md5=0ff3add4a4197018a97723a45a8a1e56
http://acikerisim.bingol.edu.tr/handle/20.500.12898/5137
Koleksiyonlar
  • Scopus İndeksli Yayınlar Koleksiyonu [1357]





Creative Commons License
DSpace@BİNGÖL by Bingöl University Institutional Repository is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 Unported License..

DSpace software copyright © 2002-2016  DuraSpace
İletişim | Geri Bildirim
Theme by 
Atmire NV
 

 



| Politika | Rehber | İletişim |

sherpa/romeo

Göz at

Tüm DSpaceBölümler & KoleksiyonlarTarihe GöreYazara GöreBaşlığa GöreKonuya GöreBy TypeBu KoleksiyonTarihe GöreYazara GöreBaşlığa GöreKonuya GöreBy Type

Hesabım

GirişKayıt

DSpace software copyright © 2002-2016  DuraSpace
İletişim | Geri Bildirim
Theme by 
Atmire NV