Show simple item record

dc.contributor.authorAydoğan, C.
dc.date.accessioned2021-04-08T12:09:13Z
dc.date.available2021-04-08T12:09:13Z
dc.date.issued2015
dc.identifier10.1016/j.chroma.2015.03.014
dc.identifier.issn00219673
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84926108077&doi=10.1016%2fj.chroma.2015.03.014&partnerID=40&md5=bb751453e16fb00e61c686daf439954c
dc.identifier.urihttp://acikerisim.bingol.edu.tr/handle/20.500.12898/4775
dc.description.abstractIn this study, an anion-exchange/hydrophobic polymethacrylate-based stationary phase was prepared for nano-liquid chromatography of small organic molecules and inorganic anions. The stationary phase was synthesized by in situ polymerization of 3-chloro-2-hydroxypropylmethacrylate and ethylene dimethacrylate inside silanized 100. μm i.d. fused silica capillary. The porogen mixture consisted of toluene and dodecanol. The pore size distrubution profiles of the resulting monolith were determined by mercury intrusion porosimetry and the morphology of the prepared monolith was investigated by scanning electron microscope. Good permeability, stability and column efficiency were observed on the monolithic column with nano flow. The produced monolithic column, which contains reactive chloro groups, was then modified by reaction with N,N-dimethyl-N-dodecylamine to obtain an anion-exchange/hydrophobic monolithic stationary phase. The functionalized monolith contained ionizable amine groups and hydrophobic groups that are useful of anion-exchange/hydrophobic mixed-mode chromatography. The final monolithic column performance with respect to anion-exchange and hydrophobic interactions was assesed by the separation of alkylbenzene derivatives, phenolic compounds and inorganic anions, respectively. Theoretical plate numbers up to 23,000 plates/m were successfully achieved in the separation of inorganic anions. © 2015 Elsevier B.V.
dc.language.isoEnglish
dc.sourceJournal of Chromatography A
dc.titleA new anion-exchange/hydrophobic monolith as stationary phase for nano liquid chromatography of small organic molecules and inorganic anions


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record