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dc.contributor.authorTopal, A. and Atamanalp, M. and Oruç, E. and Kirici, M. and Kocaman, E.M.
dc.date.accessioned2021-04-08T12:09:23Z
dc.date.available2021-04-08T12:09:23Z
dc.date.issued2014
dc.identifier10.1016/j.tice.2014.09.001
dc.identifier.issn00408166
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84920002974&doi=10.1016%2fj.tice.2014.09.001&partnerID=40&md5=33fc29643d5271de5de5d8be9f98fc97
dc.identifier.urihttp://acikerisim.bingol.edu.tr/handle/20.500.12898/4826
dc.description.abstractWe investigated apoptotic effects and changes in glucose-6-phosphate dehydrogenase (G6PD) enzyme activity in liver and gill tissues of fish exposed to chlorpyrifos. Three different chlorpyrifos doses (2.25, 4.5 and 6.75. μg/L) were administrated to rainbow trout at different time intervals (24, 48, 72 and 96. h). Acute exposure to chlorpyrifos showed time dependent decrease in G6PD enzyme activity at all concentrations (. p<. 0.05). Immunohistochemical results showed that chlorpyrifos caused mucous cell loss in gill tissue and apoptosis via caspase-3 activation in fish. The present study suggested that chlorpyrifos inhibits G6PD enzyme and causes mucous cell loss in gill and apoptosis in gill and liver tissues. © 2014 Elsevier Ltd.
dc.language.isoEnglish
dc.sourceTissue and Cell
dc.titleApoptotic effects and glucose-6-phosphate dehydrogenase responses in liver and gill tissues of rainbow trout treated with chlorpyrifos


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