Apoptotic effects and glucose-6-phosphate dehydrogenase responses in liver and gill tissues of rainbow trout treated with chlorpyrifos

dc.contributor.author	Topal, A. and Atamanalp, M. and Oruç, E. and Kirici, M. and Kocaman, E.M.
dc.date.accessioned	2021-04-08T12:09:23Z
dc.date.available	2021-04-08T12:09:23Z
dc.date.issued	2014
dc.identifier	10.1016/j.tice.2014.09.001
dc.identifier.issn	00408166
dc.identifier.uri	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920002974&doi=10.1016%2fj.tice.2014.09.001&partnerID=40&md5=33fc29643d5271de5de5d8be9f98fc97
dc.identifier.uri	http://acikerisim.bingol.edu.tr/handle/20.500.12898/4826
dc.description.abstract	We investigated apoptotic effects and changes in glucose-6-phosphate dehydrogenase (G6PD) enzyme activity in liver and gill tissues of fish exposed to chlorpyrifos. Three different chlorpyrifos doses (2.25, 4.5 and 6.75. μg/L) were administrated to rainbow trout at different time intervals (24, 48, 72 and 96. h). Acute exposure to chlorpyrifos showed time dependent decrease in G6PD enzyme activity at all concentrations (. p<. 0.05). Immunohistochemical results showed that chlorpyrifos caused mucous cell loss in gill tissue and apoptosis via caspase-3 activation in fish. The present study suggested that chlorpyrifos inhibits G6PD enzyme and causes mucous cell loss in gill and apoptosis in gill and liver tissues. © 2014 Elsevier Ltd.
dc.language.iso	English
dc.source	Tissue and Cell
dc.title	Apoptotic effects and glucose-6-phosphate dehydrogenase responses in liver and gill tissues of rainbow trout treated with chlorpyrifos

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