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Inhibitory effects of oxytocin and oxytocin receptor antagonist atosiban on the activities of carbonic anhydrase and acetylcholinesterase enzymes in the liver and kidney tissues of rats

dc.contributor.authorKocyigit, U.M. and Taşkıran, A.Ş. and Taslimi, P. and Yokuş, A. and Temel, Y. and Gulçin, İ.
dc.date.accessioned2021-04-08T12:07:47Z
dc.date.available2021-04-08T12:07:47Z
dc.date.issued2017
dc.identifier10.1002/jbt.21972
dc.identifier.issn10956670
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85033234274&doi=10.1002%2fjbt.21972&partnerID=40&md5=457bc33c6fb9ffd5725accea3a903cd4
dc.identifier.urihttp://acikerisim.bingol.edu.tr/handle/20.500.12898/4443
dc.description.abstractThe aim of this study was to investigate the effects of oxytocin (OT), atosiban, which is an OT receptor antagonist, and OT-atosiban chemicals injected to rats on the activities of carbonic anhydrase (CA) and acetylcholinesterase (AChE) enzymes in liver and kidney tissues of rats. For this purpose, four different groups, each consisting of six rats (n = 6), were formed (control group, OT administered group, atosiban administered group, and both OT and atosiban administered group). The rats were necropsied 60 min after intraperitoneal injection of chemicals into the rats. Liver tissues of rats were extracted. CA and AChE enzyme activities were measured for each tissue by using hydratase, esterase, and acetylcholiniodide methods. Activity values for each enzyme obtained were statistically calculated. © 2017 Wiley Periodicals, Inc.
dc.language.isoEnglish
dc.sourceJournal of Biochemical and Molecular Toxicology
dc.titleInhibitory effects of oxytocin and oxytocin receptor antagonist atosiban on the activities of carbonic anhydrase and acetylcholinesterase enzymes in the liver and kidney tissues of rats


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