Determination of comparative biological activities of silver nanoparticles formed by biological synthesis using Achillea Vermicularis

Abstract

Several researchers examined the production of nano-particles for their potential commercial advantages. Hazardous manufacturing methods of synthesizing nano-particles chemically have directed the research towards biological systems in producing nano-particles. The present study would explore the anti-bacterial property, anti-oxidation and anticancer activities of silver nano-particles with Achillea vermucularis in water extracts under different two temperatures. Furthermore, this study would examine the consequences of silver nano-particles, which affect human health and PC3 cell lines. Silver nano-particles have enormous uses due to their beneficial properties. Silver nano-particles are used in medicinal, industrial, nutritional, cosmetic, detergent, and medical devices. The biologically synthesized Silver nanoparticles were performed with redox. AvAgNPs were also characterized by UV–visible spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The biologically synthesized AvAgNPs showed effective antibacterial activity against Gram negative (Escherichia coli) and Gram positive (Liesteria monocytogenes, Staphylococus aureus) bacteria and yeast (Saccormyces ceravisae). WST assay analysis indicated potential anticancer characteristics. Antioxidant activity of all AvAgNPs were determined by total phenolic, total flavonoid, DPPH reduction activity, metal chelating activity, hydrogen peroxide reduction activity tests. Results indicated that AvAgNPs had potential antioxidant activity. Nano-particles collected by green synthesis could be a major source in commercial fields, therefore, silver nano-particles with Achillea vermucularis could be a good approach. The results of the present study demonstrated the potential of green synthesis of silver nanoparticles in reducing toxicity while retaining their antibacterial activities and boosting antioxidant activity of the extract. © 2018, Pakistan Botanical Society. All rights reserved.