Enzymatic synthesis of 5-amino quinoline oligomers and evaluation of
their free radical scavenging activity

dc.contributor.author	Bilici, Ali and Gecibesler, Ibrahim Halil and Kaya, Ismet
dc.date.accessioned	2021-04-02T12:03:42Z
dc.date.available	2021-04-02T12:03:42Z
dc.date.issued	2017
dc.identifier	10.1139/cjc-2016-0210
dc.identifier.issn	0008-4042
dc.identifier.uri	http://acikerisim.bingol.edu.tr/handle/20.500.12898/2532
dc.description.abstract	The compound 5-aminoquinoline (AQ) was treated with horseradish peroxidase (HRP) and H2O2 in a reaction medium containing a dioxane: phosphate buffer mixture (70:30). Products (OAQ) with a degree of polymerization ranging from 4 to 12 were obtained. H-1 NMR, FTIR, UV-vis, SEM, TG-DTA, DSC, XRD analysis, and conductivity measurements were conducted for characterization of OAQ. Compared with a monomer, OAQ showed higher thermal stability. After heating to 1000 degrees C, 46\% of the initial weight of the OAQ remained. The antioxidant efficiencies of the monomer and oligomer were evaluated by the typical spectrophotometric method such as the bleaching of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals. OAQ showed improved DPPH activity compared with the AQ monomer.
dc.language.iso	English
dc.source	CANADIAN JOURNAL OF CHEMISTRY
dc.title	Enzymatic synthesis of 5-amino quinoline oligomers and evaluation of their free radical scavenging activity
dc.type	Article

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